Happy new year 2025!
Thanks to everyone who participated in Folding@home this past year, and happy new year to you and yours! With your help, we've made a lot of progress towards understanding biology and informing new…
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
News
411 itemsNews of the research projects that Gridcoin pays for and of the Gridcoin releases, newest first. Press releases that companies pay to publish here are in the list too, marked as sponsored: Gridcoinstats does not write them and does not stand behind what they say.
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
sr2sieve wu runtime increased
I increased the runtime for sr2sieve workunits. They should now run twice as long as before.
sr2sieve wu generation
I changed the workunit generation for sr2sieve workunits, workunits which are named sr2_*. The sieve range is now smaller and workunits are running faster. With this they are fitting also better die old CPUs and ARM processors.
An allosteric glue
There has been growing interest in developing drugs that bind two or more proteins to “glue” them together. Tacrolimus (aka FK506) is a famous example. Tacrolimus is an immune-suppressant that is…
P75 ECM factor!
User user3928 found a 75-digit prime factor of an XYYXF number using ECM. This is the largest ECM factor found this year, and the 8th largest of all time.
Better folding through biased simulations
A central goal of Folding@home is to use distributed computing to solve problems that would otherwise be intractable. Protein folding is a terrific problem to address with this approach: by spawning…
Predicting drugs’ lipophilicity with Folding@home
Computational chemistry and machine learning continue to play an increasing role in drug discovery. One advance has been the increased accuracy with which we can predict the affinity of a…
Configuration continue
Hi, the configuration of ODLK1 in new server is continuing. Unfortunately we needed to compile all applications of assimilator and verificator as new OS was not compatible with the previous and use the latest BOINC tree for that. Please do not activate now the tasks elaboration has there are other actions we need to complete the migration. There will be a news when all it ok. Thanks
Peptide and protein design
Peptides are short proteins. For proteins, one typically envisions a long chain of amino acids that has folded up on itself to form a compact blob that is capable of performing some function, like…
Function of a cryptic pocket
One of the Bowman lab’s major foci is on finding and targeting cryptic pockets. Cryptic pockets are absent in experimentally derived structures of what a protein typically looks like but open up due…
The Bowman Lab Rig
Folding@home is an unmatched resource for running molecular dynamics simulations on a massive scale. The need for significant computational resources doesn't end with data generation though, as…
Project progress and summer period // Avance del proyecto y período estival
Dear volunteers, First of all, please excuse me because I wanted to send this message a week ago, but I was not able to do so. As you have seen these days, just like last year, we are entering the summer period, and the rate of sending simulations will be affected. We hope that it does not stop completely, but the sent tasks will be reduced. I take this opportunity to update the results of the last months: you have been optimizing one of the most used human ventricle models: the O'Hara and…
Improving protein design on Folding@home
The protein design field has been making great strides with the advent of new machine learning tools trained on large databases of protein structures and sequences. While designs coming from these…
Tackling Condensates
In recent years, scientists have identified a new type of compartment in cells, often called a condensate. These condensates form when weakly interacting proteins and RNA molecules segregate…
New software release!
We’re delighted to announce the full release of our new client software! We named this release “Bastet” after the Ancient Egyptian goddess associated with protection from disease. You can download…
Connecting with single molecule experiments
Our new work shows how to predict the results of single molecule experiments from large simulations, like those performed on Folding@home. Showing that simulations are consistent with experiments is…
Towards physics-based precision medicine
The goal of precision medicine is to utilize our knowledge of the molecular causes of disease to better diagnose and treat patients. In the precision medicine framework, diseases are subdivided by…
Electrical work 3
I just being informed now that tomorrow 29/05/2024 in my area there will be another electrical power off from 9:00 to 16:00!!!! This means that battery power supply cannot handle 7 hours of power failure, so I need to program that the server shot down automatically before 9:00 to preserve it. It need to be manually power on and this could be done at 19:00. Sorry for the problems. Thanks
BOINC Pentathlon - Thank you!
Thank you to all the BOINC Pentathlon participants who devoted their time and computing power to NFS@Home, and to SETI.Germany for organizing this event. We look forward to next time!
How does ApoE cause Alzheimer’s disease?
A number of active projects on Folding@home right now aim to understand how different forms of the protein apolipoprotein E (ApoE) determine one’s risk of developing Alzheimer’s disease. Alzheimer’s…
Electrical work 2
It seems that in my area electrical works are every month! On 16/05/2024 from 9:00 to 13:00 there is no electrical power in the area again, so no connection to server (power supply should be able to carry the 4h of power off and still run the server, but without connection to internet). Thanks
BOINC Pentathlon
Welcome BOINC Pentathlon participants. NFS@Home has been chosen for the Javelin Throw discipline starting May 10 at midnight UTC.
Some issues
I just see today that the OS update of some days ago has stopped something in connection. Now I reboot all to be sure new kernel were loaded. Actually log seems good, so I hope that the Boinc activity is restored good. Thanks
AlphaFold opens new opportunities for Folding@home
Folding@home has long sought to understand how proteins self-assemble, or fold, into their functional structures and what the functional implications of dynamics within the context of a folded…